Andrew McCutchen homered leading off the bottom of the 12th inning to lift the Pittsburgh Pirates to a 4-3 victory over the Milwaukee Brewers on Tuesday night.
McCutchen hit a 2-2 pitch from Mike Fiers (0-2) into the right-center field stands for his fifth home run of the season and the fourth game-ending shot of his career.
Pittsburgh's Jose Tabata had three hits, Russell Martin hit two doubles and Neil Walker had two hits.
Vin Mazzaro (2-0) pitched two scoreless innings to help the Pirates beat the Brewers for the just the second time in their last 12 meetings. Milwaukee had won five straight games at PNC Park.
Ryan Braun had three hits, including a pair of doubles, for the Brewers.